Description

Fmoc-2-Aminobenzene-1,4-Dicarboxylic Acid is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for introducing a rigid, aromatic dicarboxylic acid moiety into peptide sequences, enabling the creation of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and advanced materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of 2-aminoterephthalic acid units into peptide chains.
• Pharmaceutical Research: Used in the discovery and development of peptide drugs, including enzyme inhibitors and receptor agonists/antagonists.
• Chemical Biology Probes: Synthesis of fluorescently labeled or bioconjugated peptides for imaging and diagnostic applications.
• Material Science: Building block for the synthesis of peptide-based polymers, organic frameworks, and supramolecular assemblies.
• Combinatorial Chemistry: A valuable scaffold for generating diverse chemical libraries for high-throughput screening.
• Academic Research: Fundamental studies in organic synthesis and peptide chemistry.

Basic Information

Product Name	Fmoc-2-Aminobenzene-1,4-Dicarboxylic Acid
CAS No.	1185298-22-9
Molecular Formula	C23H17NO6
Molecular Weight	403.38 g/mol
Synonyms	Fmoc-2-Aminoterephthalic Acid; N-(9-Fluorenylmethoxycarbonyl)-2-aminoterephthalic Acid; 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]terephthalic Acid; Fmoc-2-ATA; Fmoc-ATPA; 2-(Fmoc-amino)terephthalic Acid; 2-[(Fmoc)amino]benzene-1,4-dicarboxylic Acid; N2-Fmoc-2-aminobenzene-1,4-dicarboxylic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-2-Aminobenzene-1,4-Dicarboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive research and development applications. Each lot is analyzed via HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.