Description

n-[2-(4-Amino-2-Fluorophenoxy)Ethyl]-N,n-Dimethylamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific fluorinated aromatic amine structure. This compound is critical for the synthesis of targeted active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and production of new APIs.
• Biochemical Research: Used in life science research for studying receptor-ligand interactions and enzyme inhibition.
• Preclinical & Clinical Trial Material: Supplied as a critical raw material for producing batches of investigational drugs for non-clinical and clinical studies.
• Process Chemistry & Scale-Up: Employed in process optimization and scale-up activities from laboratory to pilot plant and commercial manufacturing.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, proprietary chemical entities for pharmaceutical partners.

Basic Information

Item	Details
Product Name	n-[2-(4-Amino-2-Fluorophenoxy)Ethyl]-N,n-Dimethylamine Dihydrochloride
CAS No.	1185297-32-8
Molecular Formula	C10H16Cl2FN2O
Molecular Weight	279.15 g/mol
Synonyms	4-Amino-2-fluoro-N-[2-(dimethylamino)ethoxy]aniline dihydrochloride; 2-Fluoro-4-[(2-(dimethylamino)ethoxy]aniline dihydrochloride; N1-[2-(Dimethylamino)ethyl]-2-fluoro-1,4-benzenediamine dihydrochloride; 1185297-32-8; 4-[(2-Dimethylaminoethoxy)-2-fluoroaniline dihydrochloride; 2-Fluoro-4-[(2-(N,N-dimethylamino)ethoxy]aniline dihydrochloride; 1-(2-Dimethylaminoethoxy)-2-fluoro-4-aminobenzene dihydrochloride
EINECS	Contact for details

Quality Control

Our n-[2-(4-Amino-2-Fluorophenoxy)Ethyl]-N,n-Dimethylamine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.