Description

1-(3-Fluoro-Benzyl)-Piperidin-4-Ylamine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in modern drug discovery and development. This compound matters because it serves as a versatile intermediate for synthesizing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutics. Pharmaceutical researchers, agrochemical developers, and advanced material scientists need this precise chemical to create new molecules with targeted biological activity. Its dihydrochloride salt form ensures enhanced stability and solubility for downstream synthetic processes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in neurological and psychiatric disorder research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development of new APIs targeting G-protein coupled receptors (GPCRs).
• Chemical Biology & Proteomics: Serves as a ligand or probe in biochemical assays and target identification studies.
• Agrochemical Research: Intermediate for developing new crop protection agents and pesticides with specific mode-of-action.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs in universities and CROs (Contract Research Organizations).
• Library Synthesis for High-Throughput Screening (HTS): Used to create diverse compound libraries for biological screening against novel targets.

Basic Information

Product Name	1-(3-Fluoro-Benzyl)-Piperidin-4-Ylamine Dihydrochloride
CAS No.	1185296-53-0
Molecular Formula	C13H20Cl2FN2
Molecular Weight	291.22 g/mol
Synonyms	4-Amino-1-[(3-fluorophenyl)methyl]piperidine dihydrochloride; 1-[(3-Fluorophenyl)methyl]-4-piperidinamine dihydrochloride; 1-(3-Fluorobenzyl)piperidin-4-amine dihydrochloride; 4-Amino-1-(3-fluorobenzyl)piperidine dihydrochloride; 1-(3-Fluorobenzyl)-4-aminopiperidine dihydrochloride; 1-(3-Fluorobenzyl)piperidin-4-ylamine dihydrochloride; 3-Fluoro-N-(piperidin-4-yl)benzylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-Benzyl)-Piperidin-4-Ylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Chloride Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.