Description

1-(Pyrimidin-2-Yl)Piperidine-3-Carboxylic Acid Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its piperidine-pyrimidine core structure, which is a privileged scaffold in medicinal chemistry for developing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates with optimized potency and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Employed in the research and development of new generation pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein function in academic and industrial R&D.

Basic Information

Product Name	1-(Pyrimidin-2-Yl)Piperidine-3-Carboxylic Acid Hydrochloride
CAS No.	1185296-02-9
Molecular Formula	C10H14N3O2·HCl
Molecular Weight	245.70 g/mol
Synonyms	1-(Pyrimidin-2-yl)piperidine-3-carboxylic acid hydrochloride; 3-Piperidinecarboxylic acid, 1-(2-pyrimidinyl)-, hydrochloride (1:1); 1-(2-Pyrimidinyl)-3-piperidinecarboxylic acid hydrochloride; Piperidine-3-carboxylic acid, 1-(pyrimidin-2-yl)-, hydrochloride; CAS 1185296-02-9
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-2-Yl)Piperidine-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.