Description

n-(1H-Indol-5-Ylmethyl)-n-(Pyridin-3-Ylmethyl)Amine Dihydrochloride is a high-purity, functionalized amine salt of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmacologically active molecules, particularly those targeting central nervous system and oncological pathways. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic research laboratories engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and oncological targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study biological pathways and protein interactions.
• Ligand Synthesis: Serves as a starting material for the preparation of complex ligands used in catalysis or diagnostic assays.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in heterocyclic and amine chemistry.
• Custom Synthesis Projects: A valuable substrate for contract manufacturing organizations (CMOs) specializing in bespoke, multi-step organic synthesis.

Basic Information

Product Name	n-(1H-Indol-5-Ylmethyl)-n-(Pyridin-3-Ylmethyl)Amine Dihydrochloride
CAS No.	1185295-06-0
Molecular Formula	C16H18N4·2HCl
Molecular Weight	339.26 g/mol (free base: 266.34 g/mol)
Synonyms	N-[(1H-Indol-5-yl)methyl]-N-(pyridin-3-ylmethyl)amine dihydrochloride; 1H-Indole-5-methanamine, N-(3-pyridinylmethyl)-, dihydrochloride; 5-[[(Pyridin-3-ylmethyl)amino]methyl]-1H-indole dihydrochloride; N-(1H-Indol-5-ylmethyl)-N-(3-pyridylmethyl)amine dihydrochloride; 1185295-06-0; (Pyridin-3-ylmethyl)-[1H-indol-5-ylmethyl]amine dihydrochloride
EINECS	Contact for details

Quality Control

Our n-(1H-Indol-5-Ylmethyl)-n-(Pyridin-3-Ylmethyl)Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC are provided with every shipment. We support cGMP compliance for advanced R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.