Description

4-Quinolinecarboxylic Acid, 6-Fluoro-2-(Trifluoromethyl)-, Ethyl Ester is a high-value fluorinated quinoline derivative, a crucial building block in modern synthetic chemistry. This compound matters for its role as a sophisticated intermediate in the development of advanced pharmaceuticals and agrochemicals, where its unique trifluoromethyl and fluoro substituents impart desirable biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of novel drug candidates, particularly in therapeutic areas like oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms to enhance efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for creating advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) development.

Basic Information

Product Name	4-Quinolinecarboxylic Acid, 6-Fluoro-2-(Trifluoromethyl)-, Ethyl Ester
CAS No.	1185292-80-1
Molecular Formula	C₁₃H₉F₄NO₂
Molecular Weight	287.21 g/mol
Synonyms	Ethyl 6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylate; 6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic Acid Ethyl Ester; 4-Carbethoxy-6-fluoro-2-trifluoromethylquinoline; Quinoline-4-carboxylic acid, 6-fluoro-2-(trifluoromethyl)-, ethyl ester; 1185292-80-1; Ethyl 6-fluoro-2-(trifluoromethyl)-4-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarboxylic Acid, 6-Fluoro-2-(Trifluoromethyl)-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.