Description

Quinoline, 4-(Bromomethyl)-2-(Trifluoromethyl)- CAS NO 1185292-61-8 is a high-value, multi-functional heterocyclic building block featuring both bromomethyl and trifluoromethyl substituents. This compound is engineered for advanced synthetic chemistry, enabling the introduction of key functional groups for molecular diversification and property modulation. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the quinoline core and fluorine atoms contribute to bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, such as OLED emitters and charge-transport molecules.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromomethyl group acts as a versatile handle for further functionalization via Suzuki, Sonogashira, or Buchwald-Hartwig reactions.

Basic Information

Product Name	Quinoline, 4-(Bromomethyl)-2-(Trifluoromethyl)-
CAS No.	1185292-61-8
Molecular Formula	C11H7BrF3N
Molecular Weight	290.08 g/mol
Synonyms	4-(Bromomethyl)-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-(bromomethyl)quinoline; 4-Bromomethyl-2-trifluoromethylquinoline; Quinoline, 4-(bromomethyl)-2-(trifluoromethyl)-; 1185292-61-8
EINECS	Contact for details

Quality Control

Every batch of Quinoline, 4-(Bromomethyl)-2-(Trifluoromethyl)- is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.