Description

4-Quinolinecarboxamide, 2-(Trifluoromethyl)- is a high-purity, specialized organic compound featuring a quinoline core substituted with a trifluoromethyl group and a carboxamide moiety. This molecular structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, antiviral, and CNS therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Organic Electronic Materials: Serves as a precursor for the development of specialty chemicals used in OLEDs or other electronic applications.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Quinolinecarboxamide, 2-(Trifluoromethyl)-
CAS No.	1185292-59-4
Molecular Formula	C11H7F3N2O
Molecular Weight	240.18 g/mol
Synonyms	2-(Trifluoromethyl)-4-quinolinecarboxamide; 2-Trifluoromethylquinoline-4-carboxamide; 4-Carbamoyl-2-(trifluoromethyl)quinoline; Quinoline-4-carboxamide, 2-(trifluoromethyl)-; 2-Trifluoromethyl-4-quinolinecarboxylic acid amide; 2-(Trifluoromethyl)quinoline-4-carboxylic acid amide; 4-Quinolinecarboxamide, 2-(trifluoromethyl)-; 1185292-59-4
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarboxamide, 2-(Trifluoromethyl)- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.