Description

[2-(5-Fluoro-1-Methyl-1H-Indol-3-Yl)Ethyl]Amine Hydrochloride is a high-purity, synthetically derived indole derivative, specifically an amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a functionalized, fluorinated indole scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly within the fields of central nervous system (CNS) agents and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially serotonin receptor modulators and kinase inhibitors.
• Biochemical Research: Used as a reference standard or a starting material in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Agrochemical Development: Potential intermediate for creating new fluorinated compounds with pesticidal or herbicidal activity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	[2-(5-Fluoro-1-Methyl-1H-Indol-3-Yl)Ethyl]Amine Hydrochloride
CAS No.	1185142-42-0
Molecular Formula	C11H14ClFN2
Molecular Weight	228.69 g/mol
Synonyms	2-(5-Fluoro-1-methyl-1H-indol-3-yl)ethan-1-amine hydrochloride; 5-Fluoro-1-methyltryptamine hydrochloride (5-F-1-MT HCl); 2-(5-Fluoro-1-methylindol-3-yl)ethylamine hydrochloride; 3-(2-Aminoethyl)-5-fluoro-1-methyl-1H-indole hydrochloride; 5-Fluoro-α-methyltryptamine hydrochloride; FMeT HCl; 1185142-42-0
EINECS	Contact for details

Quality Control

Our [2-(5-Fluoro-1-Methyl-1H-Indol-3-Yl)Ethyl]Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.