Description

3-[4-(Trifluoromethyl)Phenyl]Morpholine Hcl is a high-purity, advanced pharmaceutical intermediate featuring a morpholine ring substituted with a trifluoromethylphenyl group. This compound is valued for its role in modulating the physicochemical properties of target molecules, particularly enhancing metabolic stability and membrane permeability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs), particularly for targeted therapies.
• Agrochemical Research: Used in developing advanced crop protection agents and herbicides with improved efficacy.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential monomer or additive in the development of specialty polymers with unique surface properties.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.

Basic Information

Product Name	3-[4-(Trifluoromethyl)Phenyl]Morpholine Hcl
CAS No.	1185140-30-0
Molecular Formula	C11H12F3NO•HCl
Molecular Weight	267.68 g/mol
Synonyms	3-(4-Trifluoromethylphenyl)morpholine hydrochloride; 4-[4-(Trifluoromethyl)phenyl]morpholin-3-one hydrochloride (tautomer); Morpholine, 3-[4-(trifluoromethyl)phenyl]-, hydrochloride; 1185140-30-0; 3-(4-(Trifluoromethyl)phenyl)morpholine HCl
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Trifluoromethyl)Phenyl]Morpholine Hcl adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.