Description

(Alphar)-3,5-Difluoro-α-Hydroxybenzeneacetic Acid 2-(2-Ethyl-4-Hydroxy-3-Methylbenzoyl)Hydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its specific hydrazide and difluorobenzeneacetic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular targeting. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of proprietary drug candidates, especially in oncology and metabolic disease research.
• Chemical Synthesis: Used in advanced organic synthesis for constructing complex molecules with hydrazide linkages and fluorinated aromatic systems.
• Agrochemical Research: Potential application as an intermediate in the development of new-generation herbicides or plant growth regulators.
• Material Science: Can be investigated for the creation of specialized polymers or ligands for metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	(Alphar)-3,5-Difluoro-α-Hydroxybenzeneacetic Acid 2-(2-Ethyl-4-Hydroxy-3-Methylbenzoyl)Hydrazide
CAS No.	1184940-47-3
Molecular Formula	C18H18F2N2O4
Molecular Weight	364.35 g/mol
Synonyms	2-(2-Ethyl-4-hydroxy-3-methylbenzoyl)hydrazinyl 2-(3,5-difluoro-2-hydroxyphenyl)-2-oxoacetate; 3,5-Difluoro-2-hydroxy-α-oxobenzeneacetic acid 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide; (Alphar)-3,5-Difluoro-2-hydroxybenzeneacetic acid (2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide; CAS 1184940-47-3; Alphar Hydrazide Derivative; DFHBA-Hydrazide; 2-(2-Ethyl-4-hydroxy-3-methylbenzoyl)-1-(3,5-difluoro-2-hydroxybenzoyl)hydrazine
EINECS	Contact for details

Quality Control

Our (Alphar)-3,5-Difluoro-α-Hydroxybenzeneacetic Acid 2-(2-Ethyl-4-Hydroxy-3-Methylbenzoyl)Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.