Description

4-Chloro-2-(Trifluoroacetyl)Aniline Hydrochloride Hydrate is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its trifluoroacetyl and aniline hydrochloride functional groups, which make it a critical building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl-substituted aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the chloro and trifluoroacetyl groups confer specific biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: An important compound for research into the introduction and behavior of fluorine atoms in organic molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	4-Chloro-2-(Trifluoroacetyl)Aniline Hydrochloride Hydrate
CAS No.	1184936-21-7
Molecular Formula	C8H6ClF3NO2 • HCl • xH2O
Molecular Weight	Contact for details
Synonyms	4-Chloro-2-(trifluoroacetyl)benzenamine hydrochloride hydrate; 2-Amino-5-chloro-α,α,α-trifluoroacetophenone hydrochloride hydrate; 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride hydrate; 4-Chloro-α,α,α-trifluoro-o-aminoacetophenone hydrochloride hydrate; 4-Chloro-2-aminobenzotrifluoride hydrochloride hydrate (derivative); TFAA-HCl Hydrate (context-specific abbreviation)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoroacetyl)Aniline Hydrochloride Hydrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of our clients in regulated industries. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under dry, inert conditions to prevent moisture absorption. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.