Description

1-(Quinazolin-4-Yl)Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic quinazoline and piperidine carboxylic acid structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and neurology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors and other targeted therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study specific biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of complex molecules for client projects.
• Library Synthesis: Utilized in the generation of diverse compound libraries for high-throughput screening against novel biological targets.

Basic Information

Product Name	1-(Quinazolin-4-Yl)Piperidine-3-Carboxylic Acid
CAS No.	1184535-87-2
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	1-(4-Quinazolinyl)-3-piperidinecarboxylic Acid; 3-Piperidinecarboxylic acid, 1-(4-quinazolinyl)-; 1-(Quinazolin-4-yl)piperidine-3-carboxylic acid; 1-(4-Quinazolyl)nipecotic Acid; 1-(Quinazolin-4-yl)nipecotic Acid; 1184535-87-2; 1-(Quinazolin-4-yl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Quinazolin-4-Yl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging away from direct light and moisture sources.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.