Description

4-Chloro-8-Fluoro-2,3-Dimethyl-Quinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated and alkylated quinoline structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and other therapeutic agents.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Intermediate: Acts as a core structure for synthesizing advanced fluorophores and functional dyes with specific photophysical properties.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Item	Details
Product Name	4-Chloro-8-Fluoro-2,3-Dimethyl-Quinoline
CAS No.	1184365-73-8
Molecular Formula	C11H9ClFN
Molecular Weight	209.65 g/mol
Synonyms	4-Chloro-8-fluoro-2,3-dimethylquinoline; 2,3-Dimethyl-4-chloro-8-fluoroquinoline; 8-Fluoro-4-chloro-2,3-dimethylquinoline; Quinoline, 4-chloro-8-fluoro-2,3-dimethyl-; 1184365-73-8; 4-Chloro-8-fluoro-2,3-dimethyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Fluoro-2,3-Dimethyl-Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.