Description

2-Fluoro-5-(3-Methylphenyl)Benzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the fluorine atom and biphenyl-like structure, enabling precise molecular design. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators where the fluorine moiety enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated aromatic cores in electronic and optoelectronic materials, contributing to improved performance in displays.
• Polymer Modification: Incorporated as a functional monomer to impart specific chemical resistance, thermal stability, or surface properties to advanced polymers.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	2-Fluoro-5-(3-Methylphenyl)Benzoic Acid
CAS No.	1184124-24-0
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2-Fluoro-5-(m-tolyl)benzoic acid; 5-(3-Methylphenyl)-2-fluorobenzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 2'-fluoro-5'-methyl-; 2'-Fluoro-5'-methyl[1,1'-biphenyl]-3-carboxylic acid; 2-Fluoro-5-(3-methylphenyl)benzoic acid; 1184124-24-0; 2-Fluoro-5-m-tolylbenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(3-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.