Description

1H-Pyrazole-4-Sulfonohydrazide is a specialized heterocyclic sulfonohydrazide building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, serving as a versatile precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where it enables the introduction of the sulfonohydrazide pharmacophore. Its application is primarily targeted at the research and development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting enzymes where the pyrazole-sulfonohydrazide moiety is critical for activity.
• Agrochemical Synthesis: Used in the creation of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe Development: Serves as a building block for synthesizing molecular probes to study biological pathways and protein functions.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal catalysis and coordination chemistry.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific functional properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring high-purity advanced intermediates.

Basic Information

Product Name	1H-Pyrazole-4-Sulfonohydrazide
CAS No.	1183491-92-0
Molecular Formula	C3H6N4O2S
Molecular Weight	162.17 g/mol
Synonyms	4-Pyrazolesulfonohydrazide; Pyrazole-4-sulfonic acid hydrazide; 1H-Pyrazole-4-sulfonic acid hydrazide; 4-Sulfonohydrazidopyrazole; 1183491-92-0; Pyrazolesulfonohydrazide; 1H-Pyrazol-4-ylsulfonohydrazide
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrazole-4-Sulfonohydrazide is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments for non-pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize exposure to moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.