Description

4-Bromo-2-([(tert-Butoxy)Carbonyl]Amino)Benzoic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, agrochemicals, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing ortho-substituted benzoic acid motifs.
• Peptidomimetic Research: Used to incorporate protected amino acid units into peptide analogs and peptidomimetics for drug discovery programs.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands and chelating agents in catalyst and material science.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Detail
Product Name	4-Bromo-2-([(tert-Butoxy)Carbonyl]Amino)Benzoic Acid
CAS No.	1183031-46-0
Molecular Formula	C12H14BrNO4
Molecular Weight	316.15 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)-4-bromobenzoic acid; Boc-4-Bromo-anthranilic acid; 4-Bromo-2-((Boc)amino)benzoic acid; 2-Amino-4-bromobenzoic acid tert-butyl carbamate; 4-Bromo-2-[(tert-butoxycarbonyl)amino]benzoic acid; 4-Br-Boc-anthranilic acid; Boc-4-Br-Abz-OH
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-([(tert-Butoxy)Carbonyl]Amino)Benzoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.