Description

3-(2,2-Difluoroethoxy)Naphthalene-2-Carboxylic Acid is a high-purity, functionalized naphthalene derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and building block in the development of novel active ingredients. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique difluoroethoxy moiety for enhanced biological activity and metabolic stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex polycyclic aromatic structures in academic and industrial research laboratories.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its carboxylic acid functionality and aromatic backbone.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	3-(2,2-Difluoroethoxy)Naphthalene-2-Carboxylic Acid
CAS No.	1183017-57-3
Molecular Formula	C₁₃H₁₀F₂O₃
Molecular Weight	252.22 g/mol
Synonyms	3-(2,2-Difluoroethoxy)-2-naphthoic acid; 2-Naphthalenecarboxylic acid, 3-(2,2-difluoroethoxy)-; 3-(2,2-Difluoroethoxy)-2-naphthalenecarboxylic acid; 1183017-57-3; 3-(2,2-Difluoroethoxy)naphthalene-2-carboxylic acid; 3-(Difluoroethoxy)naphthalene-2-carboxylic acid; 3-(2,2-Difluoroethoxy)naphthalene-2-carboxylic acid (CAS 1183017-57-3)
EINECS	Contact for details

Quality Control

Our 3-(2,2-Difluoroethoxy)Naphthalene-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.