Description

2-(4-Fluorophenyl)-2,3-Dihydro-1H-Indene-2-Carboxylic Acid is a high-purity, synthetically valuable indane derivative featuring a fluorinated aromatic system. This compound serves as a critical pharmaceutical intermediate and versatile building block for advanced organic synthesis, enabling the development of novel active molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create chiral ligands and organocatalysts for asymmetric synthesis applications.
• Material Science Precursor: Intermediate in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and biochemical probe design.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	2-(4-Fluorophenyl)-2,3-Dihydro-1H-Indene-2-Carboxylic Acid
CAS No.	1181643-41-3
Molecular Formula	C₁₆H₁₃FO₂
Molecular Weight	256.27 g/mol
Synonyms	2-(4-Fluorophenyl)indane-2-carboxylic Acid; 2-(p-Fluorophenyl)-2,3-dihydro-1H-indene-2-carboxylic Acid; 2-(4-Fluorophenyl)-2,3-dihydro-1H-indene-2-carboxylic Acid; 2-(4-Fluorophenyl)indan-2-carboxylic Acid; 4-Fluoro-α,2-dihydro-1H-indene-2-acetic Acid (tautomeric form); 1181643-41-3; FC-IDA; Fluorophenyl Indane Carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-2,3-Dihydro-1H-Indene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.