Description

(1R)-1-Phenylprop-2-En-1-Amine Hcl CAS NO 1181394-16-0 is a chiral amine hydrochloride salt of significant interest in advanced organic synthesis. This compound serves as a crucial chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity in industrial processes.
• Agrochemical Synthesis: Serves as a building block for developing chiral active ingredients in herbicides, fungicides, and insecticides.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry research for exploring new synthetic routes.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(1R)-1-Phenylprop-2-En-1-Amine Hydrochloride
CAS No.	1181394-16-0
Molecular Formula	C9H12ClN
Molecular Weight	169.65 g/mol
Synonyms	(R)-1-Phenylallylamine hydrochloride; (1R)-1-Phenyl-2-propen-1-amine hydrochloride; (R)-α-Methylbenzylamine allyl derivative HCl; (R)-1-Amino-1-phenyl-2-propene hydrochloride; (R)-1-Phenylprop-2-en-1-amine HCl; (R)-Homoallylamine benzene hydrochloride; (R)-1-Phenylallylamine HCl; Allyl-(R)-α-methylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1R)-1-Phenylprop-2-En-1-Amine HCl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by HPLC, identity confirmation by IR and NMR, and assay by titration. Certificates of Analysis (COA) with detailed specifications are provided to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.