Description

(R)-N,n-Diethylpyrrolidin-3-Amine Dihydrochloride CAS NO 1181083-20-4 is a high-purity chiral amine salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined pyrrolidine scaffold essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific (R)-enantiomer configuration is crucial for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Academic and R&D Chemistry: A valuable reagent for methodological studies in organic chemistry, enabling the exploration of new synthetic routes to nitrogen-containing heterocycles.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Item	Details
Product Name	(R)-N,n-Diethylpyrrolidin-3-Amine Dihydrochloride
CAS No.	1181083-20-4
Molecular Formula	C8H20Cl2N2
Molecular Weight	215.16 g/mol
Synonyms	(R)-3-(Diethylamino)pyrrolidine dihydrochloride; (R)-N,N-Diethyl-3-pyrrolidinamine dihydrochloride; (3R)-N,N-Diethylpyrrolidin-3-amine dihydrochloride; (R)-3-Diethylaminopyrrolidine dihydrochloride; (R)-1,1-Diethyl-3-aminopyrrolidinium chloride
EINECS	Contact for details

Quality Control

Our (R)-N,n-Diethylpyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.