Description

2-n-Boc-Propane-1,2-Diamine-Hcl is a protected diamine derivative, specifically the hydrochloride salt of the tert-butyloxycarbonyl (Boc)-protected 1,2-diaminopropane. This compound is a crucial high-purity building block in organic synthesis, valued for its role in introducing a chiral diamine moiety while providing orthogonal protection for amine functionalities. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those requiring a propylenediamine backbone.
• Ligand Synthesis: Used to prepare chiral ligands for asymmetric catalysis in the production of enantiomerically pure compounds.
• Peptidomimetics & Bioconjugation: Serves as a protected linker or spacer molecule in the design of peptide analogs and bioconjugates.
• Organic Synthesis Building Block: Provides a versatile, protected diamine unit for multi-step synthetic routes in academic and industrial R&D.
• Agrochemical Research: Employed in the development of novel, high-value crop protection agents and specialty chemicals.

Basic Information

Product Name	2-n-Boc-Propane-1,2-Diamine-Hcl
CAS No.	1179361-32-0
Molecular Formula	C8H19ClN2O2
Molecular Weight	210.70 g/mol
Synonyms	1,2-Diaminopropane, N-Boc derivative hydrochloride; (R/S)-1,2-Diaminopropane N-Boc hydrochloride; 1-Boc-1,2-diaminopropane hydrochloride; tert-Butyl (1,2-diaminopropyl)carbamate hydrochloride; 2-[(tert-Butoxycarbonyl)amino]propylamine hydrochloride; Propane-1,2-diamine, N-Boc protected HCl salt; 1,2-Propanediamine, N1-Boc, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-n-Boc-Propane-1,2-Diamine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.