Description

tert-Butyl 1-Oxa-4,9-Diazaspiro[5.5]Undecane-9-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is a critical building block in modern medicinal chemistry, valued for its unique structural framework that enables the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compounds with potential biological activity.
• API Synthesis: Serves as a building block in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for target identification and validation.
• Process Chemistry Development: Used in route scouting and optimization for scalable manufacturing processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical innovation.

Basic Information

Product Name	tert-Butyl 1-Oxa-4,9-Diazaspiro[5.5]Undecane-9-Carboxylate Hydrochloride
CAS No.	1179340-30-7
Molecular Formula	C14H27ClN2O3
Molecular Weight	306.83 g/mol
Synonyms	9-Boc-1-oxa-4,9-diazaspiro[5.5]undecane hydrochloride; 1-Oxa-4,9-diazaspiro[5.5]undecane-9-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride; tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate HCl; 1-Oxa-4,9-diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester hydrochloride; Spirocyclic amine hydrochloride intermediate; Boc-protected diazaspiro compound hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Oxa-4,9-Diazaspiro[5.5]Undecane-9-Carboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.