Description

2-Chloro-5-(4-Methylphenyl)Benzoic Acid is a high-purity, synthetically valuable benzoic acid derivative characterized by its chlorinated and methylphenyl-substituted aromatic structure. This compound serves as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting inflammation and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors and liquid crystal compounds due to its rigid, substituted aromatic system.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific halogenated benzoic acid derivatives.

Basic Information

Product Name	2-Chloro-5-(4-Methylphenyl)Benzoic Acid
CAS No.	1179168-49-0
Molecular Formula	C14H11ClO2
Molecular Weight	246.69 g/mol
Synonyms	2-Chloro-5-(p-tolyl)benzoic acid; 5-(4-Methylphenyl)-2-chlorobenzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-chloro-5'-methyl-; 2'-Chloro-5'-methyl[1,1'-biphenyl]-2-carboxylic acid; Benzoic acid, 2-chloro-5-(4-methylphenyl)-; 2-Chloro-5-(4-methylphenyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(4-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.