Description

2-(2,2-Difluoroethanesulfonyl)Benzoic Acid is a high-purity, specialized organic intermediate featuring a unique difluoroethanesulfonyl moiety attached to a benzoic acid core. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific fluorine substitution pattern is essential for modulating biological activity and physicochemical properties. It is primarily sought after by research institutions and industrial manufacturers in the life sciences sector for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers with tailored surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to develop novel ligands for catalytic processes in fine chemical manufacturing.
• Fluorinated Compound Library: An essential component for constructing diverse screening libraries in medicinal chemistry for drug discovery programs.

Basic Information

Product Name	2-(2,2-Difluoroethanesulfonyl)Benzoic Acid
CAS No.	1178636-79-7
Molecular Formula	C9H6F2O4S
Molecular Weight	248.21 g/mol
Synonyms	2-[(2,2-Difluoroethyl)sulfonyl]benzoic acid; Benzoic acid, 2-[(2,2-difluoroethyl)sulfonyl]-; 2-(2,2-Difluoroethylsulfonyl)benzoic acid; 2-[(2,2-Difluoroethane)sulfonyl]benzoic Acid; 1178636-79-7; 2-(2,2-Difluoroethanesulfonyl)Benzoate
EINECS	Contact for details

Quality Control

Our production of 2-(2,2-Difluoroethanesulfonyl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.