Description

(3-Bromo-2-Fluorophenyl)Methanamine Hydrochloride is a high-purity, halogenated benzylamine hydrochloride salt, a crucial building block in modern organic synthesis. Its value lies in its dual functionalization, providing both a reactive amine handle and halogen substituents for further cross-coupling and derivatization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized monomers for specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects requiring specific halogen and amine functionality.

Basic Information

Product Name	(3-Bromo-2-Fluorophenyl)Methanamine Hydrochloride
CAS No.	1177559-63-5
Molecular Formula	C7H8BrClFN
Molecular Weight	248.50 g/mol
Synonyms	1-(3-Bromo-2-fluorophenyl)methanamine hydrochloride; (3-Bromo-2-fluorobenzyl)amine hydrochloride; α-Amino-3-bromo-2-fluorotoluene hydrochloride; 3-Bromo-2-fluorobenzylamine hydrochloride; 2-Fluoro-3-bromobenzylamine HCl; 1-(3-Bromo-2-fluorophenyl)-N-methylmethanamine hydrochloride (related); Benzenemethanamine, 3-bromo-2-fluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Bromo-2-Fluorophenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and ISO-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.