Description

4-Chloro-5-Methyl-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted drug candidates, especially within oncology and anti-inflammatory research pipelines.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery.
• Kinase Inhibitor Development: Used in the construction of core structures for potential kinase inhibitors, a major class of therapeutic proteins.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in R&D and manufacturing settings.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for the preparation of complex fused pyrimidine derivatives.

Basic Information

Product Name	4-Chloro-5-Methyl-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	1177447-31-2
Molecular Formula	C9H8ClN3O
Molecular Weight	209.63 g/mol
Synonyms	4-Chloro-5-methyl-5,6-dihydro-8H-pyrido[2,3-d]pyrimidin-7-one; 4-Chloro-5-methyl-8H-pyrido[2,3-d]pyrimidin-7(5H)-one; 1177447-31-2; 4-Chloro-5-methyl-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-chloro-5-methyl-5,6-dihydro-; 4-Chloro-5-methyl-5,6-dihydro-8H-pyrido[2,3-d]pyrimidin-7-one
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methyl-5,6-Dihydropyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.