Description

5-(Aminomethyl)-3-(4-Chlorophenyl)-1,3-Oxazolidin-2-One Hydrochloride is a high-purity, specialized organic salt with significant utility as a key pharmaceutical intermediate. Its value lies in its defined chemical structure, which serves as a crucial building block for the synthesis of more complex active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of specific, client-requested APIs or advanced intermediates under cGMP conditions.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Process Chemistry Development: Acts as a starting material for scaling up and optimizing synthetic routes in pilot plant and commercial manufacturing settings.

Basic Information

Product Name	5-(Aminomethyl)-3-(4-Chlorophenyl)-1,3-Oxazolidin-2-One Hydrochloride
CAS No.	1177315-26-2
Molecular Formula	C10H12ClN2O2•HCl
Molecular Weight	261.13 g/mol (Free base: 224.67 g/mol)
Synonyms	3-(4-Chlorophenyl)-5-(aminomethyl)-2-oxazolidinone hydrochloride; 5-(Aminomethyl)-3-(4-chlorophenyl)-2-oxazolidinone monohydrochloride; (5-Aminomethyl-3-(4-chlorophenyl)-2-oxazolidinone hydrochloride; 1,3-Oxazolidin-2-one, 5-(aminomethyl)-3-(4-chlorophenyl)-, hydrochloride (1:1); CAS 1177315-26-2
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-3-(4-Chlorophenyl)-1,3-Oxazolidin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total impurities ≤ 3.0%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.