Description

{[1-(4-Fluorophenyl)-1H-Tetrazol-5-Yl]Methyl}Amine Hydrochloride is a high-purity, synthetically valuable organic intermediate characterized by its tetrazole and fluorinated aromatic structure. This compound is essential for pharmaceutical research and development, serving as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique heterocyclic scaffold into new molecular entities. The hydrochloride salt form offers enhanced stability and handling properties for synthetic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation, where the tetrazole moiety can act as a bioisostere for carboxylic acids.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of fluorinated tetrazole derivatives.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Peptidomimetics: The tetrazole ring is used to construct peptidomimetic compounds for medicinal chemistry applications.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with specific electronic or photonic properties.

Basic Information

Product Name	{[1-(4-Fluorophenyl)-1H-Tetrazol-5-Yl]Methyl}Amine Hydrochloride
CAS No.	1177290-00-4
Molecular Formula	C8H9FN5•HCl
Molecular Weight	231.65 g/mol
Synonyms	5-(Aminomethyl)-1-(4-fluorophenyl)-1H-tetrazole hydrochloride; 1-(4-Fluorophenyl)-1H-tetrazole-5-methanamine hydrochloride; (1-(4-Fluorophenyl)-1H-tetrazol-5-yl)methanamine hydrochloride; [1-(4-Fluorophenyl)-1H-tetrazol-5-yl]methylamine hydrochloride; 4-Fluorophenyltetrazole methylamine HCl; FPTZ-amine HCl; 1177290-00-4 (CAS)
EINECS	Contact for details

Quality Control

Our {[1-(4-Fluorophenyl)-1H-Tetrazol-5-Yl]Methyl}Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support compliance with relevant guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and desiccated to prevent degradation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.