Description

5-(Benzylamino-Methyl)-Pyrrolidin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a pyrrolidinone core with a benzylamino-methyl substituent. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development chemists and production teams in the pharmaceutical and biotechnology industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in neurological and psychiatric disorder research.
• API Synthesis: Serves as a crucial building block for constructing complex molecular architectures of potential Active Pharmaceutical Ingredients.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Biochemical Research: Potential use as a ligand or modifier in biochemical assays and probe development.

Basic Information

Product Name	5-(Benzylamino-Methyl)-Pyrrolidin-2-One
CAS No.	1177276-81-1
Molecular Formula	C13H18N2O
Molecular Weight	218.30 g/mol
Synonyms	5-[(Benzylamino)methyl]pyrrolidin-2-one; 5-(Benzylaminomethyl)-2-pyrrolidinone; 1-(Benzylamino)-4-aminobutane-4-lactam; N-Benzyl-5-aminomethyl-2-pyrrolidinone; 5-(Benzylaminomethyl)pyrrolidin-2-one; Pyrrolidin-2-one, 5-[(benzylamino)methyl]-; 1177276-81-1
EINECS	Contact for details

Quality Control

Our 5-(Benzylamino-Methyl)-Pyrrolidin-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.