Description

1-(2,2,2-Trifluoroethyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its piperidine core and trifluoroethyl functional group. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting the central nervous system. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug molecules, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique trifluoromethylated amine structure.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex chemical libraries and specialized fine chemicals.
• Active Pharmaceutical Ingredient (API) Development: Employed in the developmental stages of new APIs requiring a fluorinated piperidine moiety.
• Bioconjugation & Probe Synthesis: Useful for creating labeled compounds or probes for biochemical and pharmacological assays.

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1177271-15-6
Molecular Formula	C7H14Cl2F3N2
Molecular Weight	263.10 g/mol
Synonyms	4-Amino-1-(2,2,2-trifluoroethyl)piperidine dihydrochloride; 1-(2,2,2-Trifluoroethyl)-4-piperidinamine dihydrochloride; 4-Piperidinamine, 1-(2,2,2-trifluoroethyl)-, dihydrochloride; 1-(Trifluoroethyl)piperidin-4-amine dihydrochloride; 1177271-15-6; 1-(2,2,2-Trifluoroethyl)piperidin-4-amine HCl salt
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoroethyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.