Description

6,7-Dimethoxy-2-(4-(Tetrahydrofuran-2-Carbonyl)Piperazin-1-Yl)Quinazolin-4(1H)-One is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is a key building block in the synthesis of complex molecules, offering significant value for medicinal chemistry and process optimization. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Process Chemistry Development: Serves as a key starting material (KSM) or intermediate for scaling up synthetic routes under GMP conditions.
• Kinase Inhibitor Synthesis: Particularly relevant in the development of targeted therapies, given its quinazolinone core structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and biochemical studies.

Basic Information

Product Name	6,7-Dimethoxy-2-(4-(Tetrahydrofuran-2-Carbonyl)Piperazin-1-Yl)Quinazolin-4(1H)-One
CAS No.	1177261-73-2
Molecular Formula	C19H24N4O5
Molecular Weight	388.42 g/mol
Synonyms	6,7-Dimethoxy-2-[4-(oxolan-2-ylcarbonyl)piperazin-1-yl]quinazolin-4(1H)-one; 2-[4-(Tetrahydrofuran-2-carbonyl)piperazin-1-yl]-6,7-dimethoxy-1H-quinazolin-4-one; 6,7-Dimethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4-ol; 1177261-73-2; UNII-9F6V2Q1J7R; 9F6V2Q1J7R; AOB67717; BDBM50393617; ZINC000003869756; AKOS025147324.
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-2-(4-(Tetrahydrofuran-2-Carbonyl)Piperazin-1-Yl)Quinazolin-4(1H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.