Description

tert-Butyl (R)-(1-Acetylpiperidin-3-yl)carbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for the synthesis of complex, biologically active molecules due to its defined stereochemistry and protected amine functionality. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated piperidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Peptidomimetic Chemistry: Serves as a constrained amino acid analog for constructing peptide-like molecules with enhanced metabolic stability.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Asymmetric Synthesis: Employed as a building block in stereoselective synthesis to introduce the (R)-configured piperidine moiety.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high chemical and optical purity.

Basic Information

Product Name	tert-Butyl (R)-(1-Acetylpiperidin-3-yl)carbamate
CAS No.	1177014-58-2
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	(R)-tert-Butyl (1-acetylpiperidin-3-yl)carbamate; (R)-3-((tert-Butoxycarbonyl)amino)-1-acetylpiperidine; tert-Butyl N-[(3R)-1-acetyl-3-piperidyl]carbamate; 1-Acetyl-3-[(tert-butoxycarbonyl)amino]piperidine, (R)-; BOC-(R)-3-Amino-1-acetylpiperidine; (R)-1-Acetyl-3-(Boc-amino)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (R)-(1-Acetylpiperidin-3-yl)carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.