Description

[1-({[(4-Fluorophenyl)Sulfonyl]Amino}Methyl)-Cyclohexyl]Acetic Acid is a high-purity, synthetic organic compound featuring a cyclohexylacetic acid core functionalized with a 4-fluorophenylsulfonamidomethyl group. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique sulfonamide and fluorinated aryl motifs.
• Protease Inhibitor Development: Serves as a core scaffold or side-chain component in the design of enzyme inhibitors, leveraging the sulfonamide group as a potential pharmacophore.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API batches under cGMP conditions.

Basic Information

Product Name	[1-({[(4-Fluorophenyl)Sulfonyl]Amino}Methyl)-Cyclohexyl]Acetic Acid
CAS No.	1176582-75-4
Molecular Formula	C15H20FNO4S
Molecular Weight	329.39 g/mol
Synonyms	1-[[(4-Fluorophenyl)sulfonylamino]methyl]cyclohexaneacetic acid; N-[(4-Fluorophenyl)sulfonyl]-1-(carboxymethyl)cyclohexanemethanamine; 1-({[(4-Fluorophenyl)sulfonyl]amino}methyl)cyclohexylacetic acid; (1-{[(4-Fluorobenzene-1-sulfonyl)amino]methyl}cyclohexyl)acetic acid; 1-({[(4-Fluorophenyl)Sulfonyl]Amino}Methyl)-Cyclohexyl]Acetic Acid; 1-[[(4-Fluorophenyl)sulfonylamino]methyl]cyclohexane-1-acetic acid; 4-Fluoro-N-[[1-(carboxymethyl)cyclohexyl]methyl]benzenesulfonamide
EINECS	Contact for details

Quality Control

Our [1-({[(4-Fluorophenyl)Sulfonyl]Amino}Methyl)-Cyclohexyl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and identity confirmation, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), identity (IR, NMR), and impurity profiles is provided with each shipment to support your regulatory and research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed when not in use to prevent absorption of atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.