Description

(R)-2-Amino-4,4-Dimethylpentan-1-Ol Hydrochloride CAS NO 1174409-88-1 is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which are crucial for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets and other specialized medicines.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure pesticides and herbicides, where the specific (R)-enantiomer can offer enhanced efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Academic & Industrial R&D: A valuable tool for chemists in both academic settings and corporate R&D departments exploring new synthetic methodologies and compound libraries.
• Fine Chemical Production: Integral to the multi-step synthesis of other high-value, specialty fine chemicals requiring a specific stereocenter.

Basic Information

Item	Details
Product Name	(R)-2-Amino-4,4-Dimethylpentan-1-Ol Hydrochloride
CAS No.	1174409-88-1
Molecular Formula	C7H18ClNO
Molecular Weight	167.68 g/mol
Synonyms	(R)-2-Amino-4,4-dimethyl-1-pentanol hydrochloride; (R)-2-Amino-4,4-dimethylpentanol HCl; (R)-4,4-Dimethyl-2-aminopentan-1-ol hydrochloride; (R)-1-Amino-3,3-dimethylbutan-2-ol hydrochloride (tautomeric form); (R)-2-Amino-4,4-dimethylpentyl alcohol hydrochloride; (R)-ADMP-HCl; (R)-tert-Leucinol hydrochloride (common name for the enantiomer of the parent amino alcohol); (R)-2-Amino-3,3-dimethylbutanol hydrochloride
EINECS	Contact for details

Quality Control

Our production of (R)-2-Amino-4,4-Dimethylpentan-1-Ol Hydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and NMR, to verify identity and purity. Certificates of Analysis (COA) detailing specific test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.