Description

2-Acetyl-5-Iodo-2H-Indazole, 95% is a high-purity, functionalized indazole derivative, a key heterocyclic building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines an acetyl group and an iodine atom on the indazole scaffold, making it a versatile precursor for cross-coupling reactions and further derivatization. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Research: Used as a building block for synthesizing new molecules with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science Precursor: Employed in the synthesis of specialized organic ligands and functional molecules for advanced materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Institutional Research: A valuable reagent for methodological studies in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-Acetyl-5-Iodo-2H-Indazole, 95%
CAS No.	1174064-60-8
Molecular Formula	C9H7IN2O
Molecular Weight	286.07 g/mol
Synonyms	5-Iodo-2-acetyl-2H-indazole; 1-(5-Iodo-1H-indazol-2-yl)ethanone; 2-Acetyl-5-iodoindazole; 2-Acetyl-5-iodo-1H-indazole; 1174064-60-8; Ethanone, 1-(5-iodo-1H-indazol-2-yl)-; 1-(5-Iodo-2H-indazol-2-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Every batch of 2-Acetyl-5-Iodo-2H-Indazole, 95% is produced and tested under a strict quality management system. We guarantee a minimum purity of 95% (by HPLC) and provide comprehensive analytical data with each shipment. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request and accompanies all commercial orders, ensuring full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to minimize moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.