Description

4-Bromo-2-Fluoroaniline Hydrochloride is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive aromatic amine group protected as a stable hydrochloride salt, which is essential for precise and efficient downstream chemical transformations. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing halogen-substituted aniline motifs.
• Agrochemical Synthesis: Building block for developing herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and functional polymers.
• Dye and Pigment Manufacturing: Intermediate for creating specialized halogenated dyes and colorants.
• Cross-Coupling Reactions: Serves as a substrate in Buchwald-Hartwig amination and other palladium-catalyzed coupling reactions to form complex biaryl amines.
• Chemical Research & Development: Versatile reagent for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	4-Bromo-2-Fluoroaniline Hydrochloride
CAS No.	1174029-29-8
Molecular Formula	C6H6BrClFN
Molecular Weight	226.47 g/mol
Synonyms	2-Fluoro-4-bromoaniline hydrochloride; 4-Bromo-2-fluoro-benzenamine hydrochloride; 1-Bromo-4-fluoro-2-aminobenzene hydrochloride; Aniline, 4-bromo-2-fluoro-, hydrochloride; 4-Bromo-2-fluoro-phenylamine hydrochloride; 2-Amino-5-bromofluorobenzene hydrochloride; 4-Bromo-2-fluoroaniline HCl
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoroaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.