Description

2-Amino-3-Ethyl-6-Fluoroquinoline Hydrochloride CAS NO 1172943-00-8 is a high-purity, functionalized quinoline derivative, a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile scaffold for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates, leveraging its fluorine and amino groups for enhanced bioactivity.
• Agrochemical Research: Used as a core structure for developing new generation pesticides and herbicides, where the quinoline moiety contributes to systemic activity.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials due to the quinoline-based conjugated system.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.
• Catalyst Ligand Synthesis: The amino and nitrogen heterocycle can be functionalized to create novel ligands for asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in medicinal chemistry programs.

Basic Information

Product Name	2-Amino-3-Ethyl-6-Fluoroquinoline Hydrochloride
CAS No.	1172943-00-8
Molecular Formula	C₁₁H₁₂ClFN₂
Molecular Weight	226.68 g/mol
Synonyms	6-Fluoro-2-amino-3-ethylquinoline hydrochloride; 3-Ethyl-6-fluoroquinolin-2-amine hydrochloride; 2-Amino-3-ethyl-6-fluoroquinoline HCl; 2-Amino-6-fluoro-3-ethylquinoline hydrochloride; 1172943-00-8; 6-Fluoro-3-ethylquinolin-2-amine hydrochloride; AEFQ hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Ethyl-6-Fluoroquinoline Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with industry standards. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing batch-specific results for all critical parameters. Custom synthesis to meet specific purity grades (e.g., >98%, >99%) and impurity profiles is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.