Description

2-Bromo-7-Methyl-1,8-Naphthyridine is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile halogenated scaffold for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing novel active ingredients, where its bromine atom offers a strategic handle for further functionalization via cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the naphthyridine core's bioactivity.
• Material Science: Serves as a monomer or ligand precursor for creating functional organic materials, such as organic light-emitting diodes (OLEDs) or metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a molecular probe or tag due to its fluorescent properties and ability to be conjugated to biomolecules.
• Academic & Industrial R&D: A versatile reagent for method development in cross-coupling (e.g., Suzuki, Buchwald-Hartwig) and other catalytic transformations.

Basic Information

Product Name	2-Bromo-7-Methyl-1,8-Naphthyridine
CAS No.	1172616-32-8
Molecular Formula	C9H7BrN2
Molecular Weight	223.07 g/mol
Synonyms	2-Bromo-7-methyl-1,8-naphthyridine; 7-Methyl-2-bromo-1,8-naphthyridine; 1,8-Naphthyridine, 2-bromo-7-methyl-; 2-Bromo-7-methyl-[1,8]naphthyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-7-Methyl-1,8-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.