Description

2-Amino-5-Chloro-3,8-Dimethylquinoline Hydrochloride is a high-purity, functionalized quinoline derivative with significant utility in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of active molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific biological pathways.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, dyes, or organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Biochemical Research: Potential use as a scaffold or probe in biochemical assays and diagnostic development due to its quinoline core.

Basic Information

Product Name	2-Amino-5-Chloro-3,8-Dimethylquinoline Hydrochloride
CAS No.	1172287-68-1
Molecular Formula	C11H12ClN2·HCl
Molecular Weight	243.14 g/mol (Free base: 206.68 g/mol)
Synonyms	5-Chloro-3,8-dimethylquinolin-2-amine hydrochloride; 2-Amino-5-chloro-3,8-dimethylquinoline HCl; 3,8-Dimethyl-5-chloroquinolin-2-amine hydrochloride; 5-Chloro-3,8-dimethyl-2-quinolinamine hydrochloride; Quinoline, 2-amino-5-chloro-3,8-dimethyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloro-3,8-Dimethylquinoline Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance with cGMP and other relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.