Description

cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Decan-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and azaspirodecane core structure. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its role in creating molecules with potential therapeutic and biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct spirocyclic frameworks, which are privileged structures in medicinal chemistry.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its unique heterocyclic structure.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and biological pathways in academic and industrial R&D.
• Catalyst Ligand Synthesis: Potential precursor for the synthesis of specialized ligands used in asymmetric catalysis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Decan-2-One
CAS No.	1172134-12-1
Molecular Formula	C19H27NO3
Molecular Weight	317.42 g/mol
Synonyms	cis-3-(2,5-Dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one; 1-Azaspiro[4.5]decan-2-one, 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-, cis-; 4-Hydroxy-8-methoxy-3-(2,5-dimethylphenyl)-1-azaspiro[4.5]decan-2-one (cis); cis-4-Hydroxy-8-methoxy-3-(2,5-dimethylphenyl)-1-azaspiro[4.5]decan-2-one; Spirocyclic Azadecanone Intermediate; 1172134-12-1
EINECS	Contact for details

Quality Control

Our production of cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Decan-2-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our facilities operate under cGMP principles where applicable, ensuring traceability and reliability for our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.