Description

7-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its benzothiophene core and trifluoromethyl-substituted carbohydrazide functional group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for oncology, CNS, and anti-infective therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Precursor: Acts as a monomer or precursor for synthesizing specialized polymers and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a biochemical tool.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for client R&D pipelines.

Basic Information

Product Name	7-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide
CAS No.	1171927-53-9
Molecular Formula	C10H7F3N2OS
Molecular Weight	260.24 g/mol
Synonyms	7-(Trifluoromethyl)benzo[b]thiophene-2-carbohydrazide; 1-Benzothiophene-2-carbohydrazide, 7-(trifluoromethyl)-; 7-Trifluoromethyl-1-benzothiophene-2-carboxylic acid hydrazide; 7-(Trifluoromethyl)benzothiophene-2-carbohydrazide; 2-Carbohydrazido-7-(trifluoromethyl)benzothiophene
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the primary container. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.