Description

4-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is a high-purity, specialized organic building block featuring a benzothiophene core with a trifluoromethyl group and a reactive carbohydrazide moiety. This compound is valued for its unique electronic properties and functional handle, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as semiconductors or OLED components.
• Chemical Synthesis Reagent: The reactive hydrazide group makes it a versatile reagent for constructing heterocyclic compounds like pyrazoles and triazoles via condensation reactions.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to develop novel chelating ligands or metal-organic frameworks (MOFs) with specific catalytic properties.

Basic Information

Product Name	4-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide
CAS No.	1171927-41-5
Molecular Formula	C10H7F3N2OS
Molecular Weight	260.24 g/mol
Synonyms	1-Benzothiophene-2-carbohydrazide, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)benzo[b]thiophene-2-carbohydrazide; 4-Trifluoromethyl-1-benzothiophene-2-carboxylic acid hydrazide; 2-Hydrazinylcarbonyl-4-(trifluoromethyl)benzothiophene; 4-(Trifluoromethyl)benzothiophene-2-carboxylic hydrazide
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)-1-Benzothiophene-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.