Description

6-Fluoro-4-Hydrazino-2-Methylquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1171871-62-7. This compound is a critical building block in the synthesis of complex molecules, valued for its unique quinoline scaffold functionalized with reactive hydrazine and fluorine groups. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Research & Development: As a crucial building block for synthesizing novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules where the quinoline core is essential for biological activity.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the creation of targeted molecular libraries for high-throughput screening.
• Agrochemical Intermediate: Potential use in the development of advanced crop protection agents and pesticides leveraging its heterocyclic structure.
• Material Science Research: Exploration as a precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its coordinating nitrogen sites.

Basic Information

Product Name	6-Fluoro-4-Hydrazino-2-Methylquinoline Hydrochloride
CAS No.	1171871-62-7
Molecular Formula	C₁₁H₁₁FN₄·HCl
Molecular Weight	238.68 g/mol (Free base)
Synonyms	2-Methyl-6-fluoro-4-hydrazinylquinoline hydrochloride; 4-Hydrazino-6-fluoro-2-methylquinoline hydrochloride; 6-Fluoro-2-methyl-4-quinolinehydrazine hydrochloride; Quinoline, 6-fluoro-4-hydrazino-2-methyl-, hydrochloride; 1171871-62-7; 6-Fluoro-4-hydrazinyl-2-methylquinoline HCl
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-4-Hydrazino-2-Methylquinoline Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Our quality system is designed to guarantee batch-to-batch consistency and reliable supply for critical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.