Description

6-Fluoro-2-Hydrazino-3-Phenylquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1171446-43-7. This compound is a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is essential for pharmaceutical manufacturers and R&D laboratories focused on creating new therapeutic agents, especially in the fields of oncology and anti-infective drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new small-molecule therapeutics.
• Oncological Agent Development: Serves as a core scaffold for creating potential kinase inhibitors and other anti-cancer compounds.
• Anti-infective Drug Synthesis: Utilized in the research and production of novel antibacterial and antiviral agents.
• Chemical Biology Probes: Employed in the development of specialized probes for studying biological processes and target identification.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	6-Fluoro-2-Hydrazino-3-Phenylquinoline Hydrochloride
CAS No.	1171446-43-7
Molecular Formula	C₁₅H₁₃FN₄·HCl
Molecular Weight	312.75 g/mol (Free base)
Synonyms	6-Fluoro-2-hydrazinyl-3-phenylquinoline hydrochloride; 3-Phenyl-6-fluoro-2-hydrazinoquinoline hydrochloride; 2-Hydrazino-6-fluoro-3-phenylquinoline HCl; 1171446-43-7; Quinoline, 6-fluoro-2-hydrazino-3-phenyl-, hydrochloride; 6-Fluoro-3-phenylquinoline-2-hydrazine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Hydrazino-3-Phenylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.