Description

2-Amino-6-Chloro-8-Methyl-3-Phenylquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1171355-84-2. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating novel therapeutic agents, especially in oncology and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for experimental and commercial drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses due to its functionalized quinoline core.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Utilized in research institutions and corporate R&D departments for developing new chemical entities.

Basic Information

Product Name	2-Amino-6-Chloro-8-Methyl-3-Phenylquinoline Hydrochloride
CAS No.	1171355-84-2
Molecular Formula	C₁₇H₁₄Cl₂N₂
Molecular Weight	317.21 g/mol
Synonyms	2-Amino-6-chloro-8-methyl-3-phenylquinoline hydrochloride; 6-Chloro-8-methyl-3-phenylquinolin-2-amine hydrochloride; 2-Amino-6-chloro-8-methyl-3-phenylquinoline HCl; 3-Phenyl-2-amino-6-chloro-8-methylquinoline hydrochloride; 1171355-84-2; 2-Quinolinamine, 6-chloro-8-methyl-3-phenyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloro-8-Methyl-3-Phenylquinoline Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.