Description

3-Amino-6-Bromoquinoline Dihydrochloride is a high-purity, halogenated quinoline derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its reactive amino and bromo functional groups.
• Agrochemical Synthesis: Serves as a precursor for developing novel fungicides or herbicides with quinoline-based structures.
• Material Science: Potential monomer or precursor for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Can be used as a probe or linker in bioconjugation chemistry for labeling biomolecules.
• Academic & Industrial R&D: Essential for methodological development in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and other catalytic transformations.

Basic Information

Product Name	3-Amino-6-Bromoquinoline Dihydrochloride
CAS No.	1171078-83-3
Molecular Formula	C9H8BrN2·2HCl
Molecular Weight	308.00 g/mol (Free base: 233.08 g/mol)
Synonyms	6-Bromo-3-quinolinamine dihydrochloride; 3-Amino-6-bromoquinoline hydrochloride (1:2); 6-Bromo-3-aminoquinoline dihydrochloride; 3-Amino-6-bromo-quinoline dihydrochloride; Quinoline, 3-amino-6-bromo-, dihydrochloride; 1171078-83-3; AKOS025311065
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Bromoquinoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.