Description

7-Chloro-2-Hydrazino-3-Phenylquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct quinoline-based structure. This compound matters for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers need it for developing new drug candidates, especially those targeting specific enzymatic pathways or receptor sites.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential therapeutic agents, including kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with targeted biological activity.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses to construct fused heterocyclic systems due to its reactive hydrazino and chloro functional groups.
• Biochemical Research: May be employed in the development of chemical probes or assay components for studying biological processes at a molecular level.
• Agrochemical Intermediate: Potential use in the research and development of new crop protection agents and pesticides.

Basic Information

Item	Detail
Product Name	7-Chloro-2-Hydrazino-3-Phenylquinoline Hydrochloride
CAS No.	1171022-53-9
Molecular Formula	C₁₅H₁₃ClN₃·HCl
Molecular Weight	308.20 g/mol (Free base: 271.74 g/mol)
Synonyms	7-Chloro-2-hydrazinyl-3-phenylquinoline hydrochloride; 3-Phenyl-7-chloroquinoline-2-hydrazine hydrochloride; 2-Hydrazino-7-chloro-3-phenylquinoline HCl; 7-Chloro-3-phenylquinoline-2-hydrazine hydrochloride; 1171022-53-9; 7-Chloro-2-hydrazino-3-phenyl-quinoline hydrochloride; Quinoline, 7-chloro-2-hydrazino-3-phenyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-Hydrazino-3-Phenylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to minimize oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.