Description

1-Methyl-3-Nitro-5-(Trifluoromethyl)-1H-Pyrazole is a high-value, multi-functional heterocyclic compound characterized by its nitro and trifluoromethyl substituents. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex molecules. It is primarily sought after by R&D and production teams in the agrochemical and pharmaceutical industries for developing novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways.
• Agrochemical Synthesis: Serves as a crucial precursor for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole core.
• Material Science Research: Used in the development of specialty chemicals, dyes, and functional materials where the trifluoromethyl group imparts unique stability and electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and cyclization processes to construct complex molecular architectures in medicinal chemistry.

Basic Information

Product Name	1-Methyl-3-Nitro-5-(Trifluoromethyl)-1H-Pyrazole
CAS No.	1170852-33-1
Molecular Formula	C5H4F3N3O2
Molecular Weight	195.10 g/mol
Synonyms	3-Nitro-1-methyl-5-(trifluoromethyl)-1H-pyrazole; 1-Methyl-3-nitro-5-(trifluoromethyl)pyrazole; 5-(Trifluoromethyl)-1-methyl-3-nitro-1H-pyrazole; 1H-Pyrazole, 1-methyl-3-nitro-5-(trifluoromethyl)-; MNTP
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-3-Nitro-5-(Trifluoromethyl)-1H-Pyrazole adheres to stringent in-process controls and final batch testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for GMP-grade intermediates and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.