Description

2-Amino-6-Fluoro-3-Phenylquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct quinoline core structure. This compound is valued for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is essential for pharmaceutical companies and research institutions focused on developing new therapeutic agents, especially in areas like oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic compounds.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in fine chemical synthesis.
• Kinase Inhibitor Development: The quinoline structure makes it relevant for research into protein kinase inhibitors, a major class of targeted cancer therapies.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Investigated for use in the development of organic electronic materials and fluorescent dyes due to its conjugated system.

Basic Information

Item	Details
Product Name	2-Amino-6-Fluoro-3-Phenylquinoline Hydrochloride
CAS No.	1170571-99-9
Molecular Formula	C15H12FN2·HCl
Molecular Weight	284.73 g/mol (Free base: 248.27 g/mol)
Synonyms	2-Amino-6-fluoro-3-phenylquinoline HCl; 6-Fluoro-3-phenylquinolin-2-amine hydrochloride; 2-Amino-6-fluoro-3-phenylquinoline monohydrochloride; 3-Phenyl-6-fluoroquinolin-2-amine hydrochloride; 1170571-99-9; 2-Quinolinamine, 6-fluoro-3-phenyl-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-Fluoro-3-Phenylquinoline Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.